QA-driven guidelines generation for bacteriotherapy

AMIA Annu Symp Proc. 2009 Nov 14:2009:509-13.

Abstract

Purpose: We propose a question-answering (QA) driven generation approach for automatic acquisition of structured rules that can be used in a knowledge authoring tool for antibiotic prescription guidelines management.

Methods: The rule generation is seen as a question-answering problem, where the parameters of the questions are known items of the rule (e.g. an infectious disease, caused by a given bacterium) and answers (e.g. some antibiotics) are obtained by a question-answering engine.

Results: When looking for a drug given a pathogen and a disease, top-precision of 0.55 is obtained by the combination of the Boolean engine (PubMed) and the relevance-driven engine (easyIR), which means that for more than half of our evaluation benchmark at least one of the recommended antibiotics was automatically acquired by the rule generation method.

Conclusion: These results suggest that such an automatic text mining approach could provide a useful tool for guidelines management, by improving knowledge update and discovery.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Bacterial Infections / drug therapy*
  • Data Mining*
  • Decision Support Techniques*
  • Electronic Data Processing
  • Humans
  • Information Storage and Retrieval
  • Practice Guidelines as Topic*
  • PubMed
  • Search Engine
  • Vocabulary, Controlled

Substances

  • Anti-Bacterial Agents