GWASs and the age of human as the model organism for autoimmune genetic research

Genome Biol. 2010;11(5):212. doi: 10.1186/gb-2010-11-5-212. Epub 2010 May 5.

Abstract

Genetic studies have identified more than 150 autoimmune loci, and next-generation sequencing will identify more. Is it time to make human the model organism for autoimmune research?

MeSH terms

  • Alleles
  • Autoimmune Diseases / genetics
  • Genetic Predisposition to Disease
  • Genetic Research*
  • Genome-Wide Association Study*
  • Humans
  • Inheritance Patterns / genetics
  • Models, Biological*
  • Mutation / genetics
  • Polymorphism, Single Nucleotide / genetics
  • Reproducibility of Results
  • Sequence Analysis, DNA
  • Time Factors