Abstract
One hundred fifty canine and feline Escherichia coli isolates associated with urinary tract infections were screened for the presence of extended-spectrum beta-lactamase (ESBL) genes. Out of 60 isolates suspected to be ESBL positive based on antimicrobial susceptibility testing, 11 ESBLs were identified, including one SHV-12 gene, one CTX-M-14 gene, and nine CTX-M-15 genes. This study provides the first report of CTX-M- and SHV-type ESBLs in dogs and cats in the United States.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Anti-Bacterial Agents / pharmacology
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Cat Diseases / microbiology*
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Cats
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DNA, Bacterial / analysis
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DNA, Bacterial / genetics
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Dog Diseases / microbiology*
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Dogs
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Escherichia coli / drug effects
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Escherichia coli / enzymology*
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Escherichia coli / genetics
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Escherichia coli Infections / microbiology
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Escherichia coli Infections / veterinary*
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Microbial Sensitivity Tests
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Polymerase Chain Reaction
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Sequence Analysis, DNA
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United States
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Urinary Tract Infections / microbiology
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Urinary Tract Infections / veterinary*
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beta-Lactamases / genetics*
Substances
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Anti-Bacterial Agents
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DNA, Bacterial
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beta-lactamase CTX-M-14
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beta-lactamase CTX-M-15
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beta-lactamase SHV-12
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beta-Lactamases