Delphian node metastasis in head and neck cancers--oracle or myth?

N Gopalakrishna Iyer; Ashok R Shaha; Alfio Ferlito; K Thomas Robbins; Jesus E Medina; Carl E Silver; Alessandra Rinaldo; Robert P Takes; Carlos Suárez; Juan P Rodrigo; Patrick J Bradley; Jochen A Werner

doi:10.1002/jso.21640

Delphian node metastasis in head and neck cancers--oracle or myth?

J Surg Oncol. 2010 Sep 15;102(4):354-8. doi: 10.1002/jso.21640.

Authors

N Gopalakrishna Iyer¹, Ashok R Shaha, Alfio Ferlito, K Thomas Robbins, Jesus E Medina, Carl E Silver, Alessandra Rinaldo, Robert P Takes, Carlos Suárez, Juan P Rodrigo, Patrick J Bradley, Jochen A Werner

Affiliation

¹ Head and Neck Service, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.

PMID: 20589710
DOI: 10.1002/jso.21640

Abstract

Delphian node (DN) refers to the pre-laryngeal or pre-cricoid nodal tissue often identified during laryngeal or thyroid surgery. The original nomenclature is based on the assumption that metastasis to this node was predictive of aggressive disease and poor outcome for patients. In this article, we review the existing literature on the topic to determine the significance of DN metastasis in laryngeal, hypopharyngeal and thyroid cancers.

Publication types

Review

MeSH terms

Head and Neck Neoplasms / mortality
Head and Neck Neoplasms / pathology*
Head and Neck Neoplasms / surgery
Humans
Hypopharyngeal Neoplasms / mortality
Hypopharyngeal Neoplasms / pathology
Hypopharyngeal Neoplasms / surgery
Laryngeal Neoplasms / mortality
Laryngeal Neoplasms / pathology
Laryngeal Neoplasms / surgery
Lymph Nodes / pathology*
Lymphatic Metastasis
Prognosis
Thyroid Neoplasms / mortality
Thyroid Neoplasms / pathology
Thyroid Neoplasms / surgery