Patients with dyscirculatory encephalopathy (DE) were examined to elucidate interhemisphere relationships by recording brain constant potential (CP) and perfusion CT. Electrophysiological characteristics were shown to relate to local brain blood flow. Dispersion of intrehemisphere CP level in DE patients proved more pronounced than in healthy subjects. Interhemisphere CP difference in temporal region significantly (p < 0.001) correlated with the time needed to reach maximum concentration of contrast agent in the frontal and temporal cortex, basal ganglia, and thalamus. Left temporal CP level positively correlated with contrast agent concentration in the above brain structures of both hemispheres and negatively with that in the right hemisphere. It is concluded that intertemporal relationships may influence vegetative nervous system that in turn changes cardiovascular function.