This study compared the relative amounts and patterns of fluoride release from six commercially available light-cured liners in artificial saliva over a 28-day period. Cavalite and two Zionomer products released relatively small amounts of fluoride. Timeline and XR Ionomer released the highest cumulative total of fluoride over time. During the last time interval (14-28 days), Timeline released the greatest amount of fluoride. Patterns of fluoride release for all materials were similar with the largest proportion of the total fluoride release being in the first 24-48 hours, followed by a dramatic reduction in release rate.