Complementary PCAF-coenzyme A mutagenesis: chemoenzymatic synthesis of a novel enlarged coenzyme A analogue and evaluation of its biological activity

Chembiochem. 2010 Oct 18;11(15):2100-3. doi: 10.1002/cbic.201000286.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acyl Coenzyme A / biosynthesis
  • Acyl Coenzyme A / chemistry*
  • Amino Acid Substitution
  • Binding Sites
  • Computer Simulation
  • Kinetics
  • Mutagenesis, Site-Directed
  • Nucleotidyltransferases / metabolism
  • Phosphotransferases (Alcohol Group Acceptor) / metabolism
  • Protein Structure, Tertiary
  • Substrate Specificity
  • p300-CBP Transcription Factors / chemistry*
  • p300-CBP Transcription Factors / genetics
  • p300-CBP Transcription Factors / metabolism

Substances

  • Acyl Coenzyme A
  • acetyl 3''-O-benzyl-coenzyme A
  • p300-CBP Transcription Factors
  • p300-CBP-associated factor
  • Phosphotransferases (Alcohol Group Acceptor)
  • dephospho-CoA kinase
  • Nucleotidyltransferases
  • pantetheine-phosphate adenylyltransferase