Transcriptomics and proteomics in the study of H1N1 2009

Lijun Zhang; Xiaojun Zhang; Qing Ma; Fang Ma; Honghao Zhou

doi:10.1016/S1672-0229(10)60016-2

Transcriptomics and proteomics in the study of H1N1 2009

Genomics Proteomics Bioinformatics. 2010 Sep;8(3):139-44. doi: 10.1016/S1672-0229(10)60016-2.

Authors

Lijun Zhang¹, Xiaojun Zhang, Qing Ma, Fang Ma, Honghao Zhou

Affiliation

¹ Department of Pharmacogenetics, Institute of Clinical Pharmacology, Central South University, Changsha 410078, China. zhanglijun1221@163.com

Abstract

Influenza A virus (H1N1) 2009, a new swine-origin influenza A virus, has been spread worldwidely and caused great public fear. High-throughput transcriptomics and proteomics methods are now being used to identify H1N1 and H1N1-host interaction. This article reviews recent transcriptomics and proteomics research in H1N1 diagnosis, treatment, and H1N1 virus-host interaction, to offer some help for further understanding the infection mechanism and controlling H1N1 transmission.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Disease Outbreaks
Gene Expression Profiling
Humans
Influenza A Virus, H1N1 Subtype / metabolism*
Influenza, Human / metabolism*
Influenza, Human / virology*
Oligonucleotide Array Sequence Analysis
Prognosis
Proteome
Proteomics / methods
RNA / genetics
RNA Interference
Reverse Transcriptase Polymerase Chain Reaction

Substances

Proteome
RNA