Abstract
We measured plasma concentration of efavirenz (EFV) in 16 HIV-infected Indian children receiving antiretroviral treatment at Government ART centres. The mean 12 hour concentration was 2.39 ug/mL (range: 0.72- 7.82 ug/mL). The majority of children treated with generic EFV at currently recommended doses had blood levels within the therapeutic range.
Publication types
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Letter
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Alkynes
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Anti-HIV Agents / pharmacokinetics*
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Anti-HIV Agents / therapeutic use
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Benzoxazines / pharmacokinetics*
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Benzoxazines / therapeutic use
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Child
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Cyclopropanes
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Drugs, Generic / pharmacokinetics*
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Drugs, Generic / therapeutic use
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Female
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HIV Infections / drug therapy*
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HIV Infections / metabolism
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Humans
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India
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Male
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Reverse Transcriptase Inhibitors / pharmacokinetics*
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Reverse Transcriptase Inhibitors / therapeutic use
Substances
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Alkynes
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Anti-HIV Agents
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Benzoxazines
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Cyclopropanes
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Drugs, Generic
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Reverse Transcriptase Inhibitors
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efavirenz