Glycomics hits the big time

Cell. 2010 Nov 24;143(5):672-6. doi: 10.1016/j.cell.2010.11.008.

Abstract

Cells run on carbohydrates. Glycans, sequences of carbohydrates conjugated to proteins and lipids, are arguably the most abundant and structurally diverse class of molecules in nature. Recent advances in glycomics reveal the scope and scale of their functional roles and their impact on human disease.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Animals
  • Biomarkers, Tumor / analysis
  • Glycolipids / analysis
  • Glycomics*
  • Glycosylation
  • Glycosyltransferases / genetics
  • Glycosyltransferases / metabolism
  • Humans
  • Neoplasms / diagnosis
  • Polysaccharides / analysis
  • Polysaccharides / metabolism
  • Protein Processing, Post-Translational
  • Proteoglycans / analysis

Substances

  • Biomarkers, Tumor
  • Glycolipids
  • Polysaccharides
  • Proteoglycans
  • Glycosyltransferases