Abstract
Cells run on carbohydrates. Glycans, sequences of carbohydrates conjugated to proteins and lipids, are arguably the most abundant and structurally diverse class of molecules in nature. Recent advances in glycomics reveal the scope and scale of their functional roles and their impact on human disease.
Copyright © 2010 Elsevier Inc. All rights reserved.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Animals
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Biomarkers, Tumor / analysis
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Glycolipids / analysis
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Glycomics*
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Glycosylation
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Glycosyltransferases / genetics
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Glycosyltransferases / metabolism
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Humans
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Neoplasms / diagnosis
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Polysaccharides / analysis
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Polysaccharides / metabolism
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Protein Processing, Post-Translational
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Proteoglycans / analysis
Substances
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Biomarkers, Tumor
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Glycolipids
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Polysaccharides
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Proteoglycans
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Glycosyltransferases