Abstract
Necrotizing soft tissue infections remain a challenging clinical problem. Delays in diagnosis, incomplete débridement of necrotic tissues, and the hemodynamic instability and end-organ failure associated with overwhelming sepsis all contribute to significant mortality. Extracorporeal support is a well-established tool to support profound cardiopulmonary failure. To broaden the indications for use, we present two cases of young adults with necrotizing soft tissue infections who sustained sepsis-induced hemodynamic collapse and required extracorporeal support to facilitate adequate tissue débridement as a bridge to recovery.
MeSH terms
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Adolescent
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Adult
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Amputation, Surgical
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Anti-Bacterial Agents / therapeutic use
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Cesarean Section / adverse effects*
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Debridement
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Extracorporeal Membrane Oxygenation*
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Female
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Humans
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Leg*
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Male
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Necrosis / complications
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Necrosis / microbiology
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Necrosis / therapy
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Shock, Septic / complications
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Shock, Septic / microbiology
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Shock, Septic / therapy*
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Soft Tissue Infections / complications
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Soft Tissue Infections / microbiology
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Soft Tissue Infections / therapy*
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Streptococcal Infections / complications
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Streptococcal Infections / therapy*
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Surgical Wound Infection / complications
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Surgical Wound Infection / microbiology
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Surgical Wound Infection / therapy*