New biocompatible thermo-reversible hydrogels from PNiPAM-decorated amyloid fibrils

Chem Commun (Camb). 2011 Mar 14;47(10):2913-5. doi: 10.1039/c0cc05126h. Epub 2011 Jan 14.

Abstract

New biocompatible temperature-responsive hydrogels have been obtained by using unprecedented low concentration of amyloid fibril-PNiPAM hybrids. The viscoelasticity of the hydrogels can be finely controlled by tuning the PNiPAM layers without changing the structure or concentration of the amyloid fibrils.

MeSH terms

  • Acrylic Resins / chemistry*
  • Amyloid / chemistry*
  • Coated Materials, Biocompatible / chemistry*
  • Hydrogels / chemistry*
  • Models, Molecular
  • Phase Transition
  • Protein Multimerization*
  • Protein Structure, Secondary
  • Temperature*

Substances

  • Acrylic Resins
  • Amyloid
  • Coated Materials, Biocompatible
  • Hydrogels
  • poly-N-isopropylacrylamide