Objective: To report two successful pregnancies after frozen-thawed ET in discontinued hormone replacement treatment cycles.
Design: Case report.
Setting: University hospital.
Patient(s): Two infertile patients.
Intervention(s): Hormone replacement treatment for endometrial preparation and frozen-thawed ET.
Main outcome measure(s): Ovarian ultrasonography, serial hormone measurements of serum E2 and P, successful pregnancy, and follow-up visit.
Result(s): One patient discontinued both E2 and P support 2 weeks after ET. The other discontinued estrogen support on the day preceding ET. No spontaneous follicle development was observed by ultrasonography, and no increase in serum P concentration was observed. Both patients became pregnant and achieved deliveries.
Conclusion(s): These two cases show that maintenance of pregnancy is possible without early hormone support in hormone replacement treatment cycles.
Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.