[Preoperative preparation, antibiotic prophylaxis and surgical wound infection in breast surgery]

Enferm Infecc Microbiol Clin. 2011 Jun-Jul;29(6):415-20. doi: 10.1016/j.eimc.2011.02.002. Epub 2011 Mar 26.
[Article in Spanish]

Abstract

Introduction: The impact of surgical wound infection on public health justifies its surveillance and prevention. Our objectives were to estimate the incidence of surgical wound infection in breast procedures and assess its protocol of antibiotic prophylaxis and preoperative preparation.

Methods: Observational multicentre prospective cohort study of incidence of surgical wound infection. Incidence was evaluated, stratified by National Nosocomial Infection Surveillance (NNIS) risk index and we calculated the standardized incidence ratio (SIR). The SIR was compared with Spanish rates and U.S. rates. The compliance and performance of the antibiotic prophylaxis and preoperative preparation protocol were assessed and their influence in the incidence of infection with the relative risk.

Results: Ten hospitals from the Comunidad de Madrid were included, providing 592 procedures. The cumulative incidence of surgical wound infection was 3.89% (95% CI: 2.3-5.5). The SIR was 1.82 on the Spanish rate and 2.16 on the American. Antibiotic prophylaxis was applied in 97.81% of cases, when indicated. The overall performance of antibiotic prophylaxis was 75%, and 53% for preoperative preparation. No association was found between infection and performance of prophylaxis or preoperative preparation (P>.05).

Conclusion: Our incidence is within those seen in the literature although it is somewhat higher than the national surveillance programs. The performance of prophylaxis antibiotic must be improved, as well as the recording of preoperative preparation data.

Publication types

  • English Abstract
  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibiotic Prophylaxis*
  • Female
  • Humans
  • Incidence
  • Male
  • Mastectomy*
  • Middle Aged
  • Preoperative Care*
  • Prospective Studies
  • Surgical Wound Infection / epidemiology*
  • Surgical Wound Infection / prevention & control*