Genomic imprinting: an obsession with depilatory mice

David Haig; Francisco Úbeda

doi:10.1016/j.cub.2011.02.027

Genomic imprinting: an obsession with depilatory mice

Curr Biol. 2011 Apr 12;21(7):R257-9. doi: 10.1016/j.cub.2011.02.027.

Authors

David Haig¹, Francisco Úbeda

Affiliation

¹ Department of Organismic and Evolutionary Biology, Harvard University, 26 Oxford Street, Cambridge, MA 02138, USA. dhaig@oeb.harvard.edu

PMID: 21481762
DOI: 10.1016/j.cub.2011.02.027

Abstract

Excessive grooming in mice has been promoted as a model of human obsessive-compulsive disorders. A recent paper adds Grb10 to the list of genes with effects on behavioral hair loss, with the added twist that this time the gene is imprinted.

MeSH terms

Animals
Disease Models, Animal
GRB10 Adaptor Protein / genetics
Genomic Imprinting*
Grooming*
Humans
Mice
Obsessive-Compulsive Disorder / genetics*

Substances

GRB10 Adaptor Protein