A new way APP mismetabolism can lead to Alzheimer's disease

EMBO Mol Med. 2011 May;3(5):247-8. doi: 10.1002/emmm.201100139. Epub 2011 Apr 27.
No abstract available

Publication types

  • Comment

MeSH terms

  • Alzheimer Disease / physiopathology*
  • Amino Acid Substitution / genetics
  • Amyloid Precursor Protein Secretases / metabolism*
  • Amyloid beta-Peptides / metabolism*
  • Amyloid beta-Protein Precursor / genetics*
  • Amyloid beta-Protein Precursor / metabolism*
  • Aspartic Acid Endopeptidases / metabolism*
  • Lead
  • Models, Biological
  • Mutant Proteins / genetics
  • Mutant Proteins / metabolism
  • Mutation, Missense*

Substances

  • Amyloid beta-Peptides
  • Amyloid beta-Protein Precursor
  • Mutant Proteins
  • Lead
  • Amyloid Precursor Protein Secretases
  • Aspartic Acid Endopeptidases
  • BACE1 protein, human