Abstract
The amino acid sequences of several, recently cloned cytokine receptors show significant homologies, primarily in their extracellular, ligand-binding domains. With one exception, their cognate cytokines mediate biological activities on a variety of hematopoietic cell types; thus we have designated the receptors as the hematopoietic receptor superfamily.
MeSH terms
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Amino Acid Sequence
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Animals
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Biological Factors / metabolism*
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Cytokines
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Humans
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Molecular Sequence Data
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Protein Conformation
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Receptors, Cell Surface / classification
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Receptors, Cell Surface / metabolism*
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Receptors, Immunologic / classification
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Receptors, Immunologic / metabolism*
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Sequence Homology, Nucleic Acid
Substances
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Biological Factors
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Cytokines
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Receptors, Cell Surface
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Receptors, Immunologic