Differences between early and late drop-outs from treatment for obsessive-compulsive disorder

J Anxiety Disord. 2011 Oct;25(7):918-23. doi: 10.1016/j.janxdis.2011.05.004. Epub 2011 May 20.

Abstract

To examine characteristics of drop-outs from treatment for obsessive-compulsive disorder (OCD), we studied 121 participants who underwent exposure or cognitive treatment, either alone or with fluvoxamine. OCD symptoms were assessed at pre-treatment, post-treatment, and at every session. No differences in attrition were found between treatment conditions. Drop-outs from treatment (n=31) were divided into early (before session 6) and late (session 6 or after) drop-outs. We found that early drop-outs had more severe OCD symptoms at termination compared to completers, whereas late drop-outs did not differ from treatment completers. Higher levels of depressive symptoms were associated with early drop-outs, and lower levels with completers. These findings suggest that individuals with high levels of pretreatment depression are at risk for early drop-out with elevated OCD symptoms. Conversly, late drop-outs may be treatment responders who drop out after experiencing substantial improvement. Implications for allocation of resources for attrition prevention are discussed.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Anti-Anxiety Agents / therapeutic use
  • Cognitive Behavioral Therapy
  • Combined Modality Therapy
  • Depressive Disorder / psychology*
  • Depressive Disorder / therapy
  • Female
  • Fluvoxamine / therapeutic use
  • Humans
  • Male
  • Middle Aged
  • Obsessive-Compulsive Disorder / drug therapy
  • Obsessive-Compulsive Disorder / psychology
  • Obsessive-Compulsive Disorder / therapy*
  • Patient Dropouts / psychology*
  • Randomized Controlled Trials as Topic
  • Treatment Outcome

Substances

  • Anti-Anxiety Agents
  • Fluvoxamine