Solubilized gramicidin A as potential systemic antibiotics

Chembiochem. 2012 Jan 2;13(1):51-5. doi: 10.1002/cbic.201100671. Epub 2011 Nov 24.

Authors

Fang Wang¹, Luoheng Qin, Christopher J Pace, Patrick Wong, Ryan Malonis, Jianmin Gao

Affiliation

¹ Department of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, MA 02461, USA.

PMID: 22113881
DOI: 10.1002/cbic.201100671

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Amino Acid Sequence
Anti-Bacterial Agents / chemistry
Anti-Bacterial Agents / pharmacology*
Antibodies, Monoclonal / chemistry
Antibodies, Monoclonal / pharmacology*
Bacillus subtilis / drug effects*
Cell Line, Tumor
Cell Proliferation / drug effects
Cell Survival / drug effects
Dose-Response Relationship, Drug
Drug Screening Assays, Antitumor
Escherichia coli / drug effects*
Gramicidin / chemistry
Gramicidin / pharmacology*
HeLa Cells
Humans
Microbial Sensitivity Tests
Models, Molecular
Molecular Sequence Data
Solubility
Staphylococcus / drug effects*
Structure-Activity Relationship

Substances

Anti-Bacterial Agents
Antibodies, Monoclonal
Gramicidin