Epstein-Barr virus-associated post-transplant lymphoproliferative disorders after allogeneic peripheral blood stem cell transplantation for Hodgkin-like adult T-cell leukemia/lymphoma

Int J Hematol. 2012 Feb;95(2):214-6. doi: 10.1007/s12185-011-0979-4. Epub 2011 Dec 16.

Abstract

A 56-year-old woman with Hodgkin-like adult T-cell leukemia/lymphoma was treated with allogeneic peripheral blood stem cell transplantation on 17 April 2009. She manifested a moderate fever on day 41. CT scanning and other examinations detected slightly swollen lymph nodes, and pathological findings of right axillary lymph nodes revealed an Epstein-Barr virus-associated post-transplant lymphoproliferative disorder. She was successfully treated with rituximab.

Publication types

  • Case Reports

MeSH terms

  • Antibodies, Monoclonal, Murine-Derived / therapeutic use
  • Antineoplastic Agents / therapeutic use
  • Epstein-Barr Virus Infections / complications*
  • Epstein-Barr Virus Infections / pathology
  • Female
  • Hematopoietic Stem Cell Transplantation*
  • Humans
  • Leukemia-Lymphoma, Adult T-Cell / therapy*
  • Lymph Nodes / pathology
  • Lymph Nodes / virology
  • Lymphoproliferative Disorders / drug therapy
  • Lymphoproliferative Disorders / pathology
  • Lymphoproliferative Disorders / virology*
  • Middle Aged
  • Rituximab
  • Transplantation, Homologous

Substances

  • Antibodies, Monoclonal, Murine-Derived
  • Antineoplastic Agents
  • Rituximab