(+)-Camphor derivative induced asymmetric [2+2] photoaddition reaction

Guolei Zhao; Chao Yang; Hongnan Sun; Run Lin; Wujiong Xia

doi:10.1021/ol203314y

(+)-Camphor derivative induced asymmetric [2+2] photoaddition reaction

Org Lett. 2012 Feb 3;14(3):776-9. doi: 10.1021/ol203314y. Epub 2012 Jan 20.

Authors

Guolei Zhao¹, Chao Yang, Hongnan Sun, Run Lin, Wujiong Xia

Affiliation

¹ State Key Lab of Urban Water Resource and Environment, the Academy of Fundamental and Interdisciplinary Sciences, Harbin Institute of Technology, Harbin 150080, China.

PMID: 22263614
DOI: 10.1021/ol203314y

Abstract

An efficient approach to construct an enantiomerically pure cyclobutane skeleton by means of the chiral auxiliary induced [2 + 2] photoaddition reactions has been described. This asymmetric photoreaction exhibited high diastereoselectivity and provided the photoadducts in excellent yields.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Camphor / analogs & derivatives*
Molecular Structure
Photochemical Processes*
Stereoisomerism

Substances

Camphor