Inflammasome and caspase-1 inhibition caused by Bcl-2 and Bcl-XL may influence cytokine responses of lipopolysaccharide-stimulated peripheral blood mononuclear cells from septic patients

Crit Care. 2012 Feb 8;16(1):410. doi: 10.1186/cc11156.
No abstract available

Publication types

  • Letter
  • Comment

MeSH terms

  • Caspase 1 / metabolism*
  • Endotoxemia / metabolism*
  • Female
  • HLA-DR Antigens / metabolism*
  • Humans
  • Interleukin-12 / blood*
  • Interleukin-1beta / metabolism*
  • Male
  • Sepsis / immunology*
  • Sepsis / metabolism*
  • Survivors*

Substances

  • HLA-DR Antigens
  • Interleukin-1beta
  • Interleukin-12
  • Caspase 1