Vestibular evoked myogenic potential in unilateral vestibular hypofunction

Acta Otolaryngol. 2012 Jul;132(7):732-8. doi: 10.3109/00016489.2012.659283. Epub 2012 Mar 11.

Abstract

Conclusion: The patients with unilateral chronic vestibular hypofunction detected by caloric test demonstrated at least some sort of altered vestibular evoked myogenic potential (VEMP) in 63.63% of the cases. The VEMP altered side was the same as the unilateral vestibular hypofunction side in 54.54% of the cases and was the opposite side in 24.24%. The VEMP test improved functional vestibular assessment in patients with unilateral caloric hypofunction.

Objectives: To analyze VEMP in patients with chronic dizziness and unilateral vestibular hypofunction and verify findings according to the side and structures involved.

Methods: This was an observational study. In all, 66 subjects were evaluated by VEMP (tone bursts/1000 Hz/100 dBnHL/bandpass filtered 10-1500 Hz/4.3 Hz rate), 33 with unilateral vestibular hypofunction, detected by caloric test and clinical data, and 33 control subjects, matched by gender and age. Amplitude of the p13-n23, asymmetry index of the amplitude, p13 and n23 latencies, p13 and n23 interaural difference and threshold were analyzed. Simple descriptive analysis was carried out using the t test, Shapiro-Wilks test, and Mann-Whitney test, p < 0.05.

Results: VEMP was altered in patients with unilateral vestibular hypofunction in 63.63% of cases. Thirteen of them were ipsilateral to the vestibular hypofunction and three were contralateral to the vestibular hypofunction. In five cases, VEMP were bilaterally altered.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acoustic Stimulation
  • Adolescent
  • Adult
  • Caloric Tests
  • Case-Control Studies
  • Dizziness / diagnosis
  • Dizziness / etiology
  • Dizziness / physiopathology*
  • Electromyography
  • Female
  • Humans
  • Male
  • Middle Aged
  • Reaction Time / physiology
  • Reproducibility of Results
  • Vestibular Diseases / complications
  • Vestibular Diseases / diagnosis
  • Vestibular Diseases / physiopathology*
  • Vestibular Evoked Myogenic Potentials / physiology*
  • Young Adult