Abstract
We have described a turn on fluorescent probe BOD-NHOH based on hydroxylamine oxidation for detecting intracellular ferric ions. The probe comprises a signal transducer of BODIPY dye and a Fe(3+)-response modulator of hydroxylamine. It is readily employed for assessing intracellular ferric ion levels, and confocal imaging is achieved successfully.
This journal is © The Royal Society of Chemistry 2012
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Boron Compounds / chemistry
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Cell Line, Tumor
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Ferric Compounds / analysis*
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Fluorescent Dyes / chemistry*
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Humans
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Hydrogen-Ion Concentration
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Hydroxylamine / chemistry*
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Ions / chemistry
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Microscopy, Confocal*
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Oxidation-Reduction
Substances
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4,4-difluoro-4-bora-3a,4a-diaza-s-indacene
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Boron Compounds
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Ferric Compounds
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Fluorescent Dyes
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Ions
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Hydroxylamine