Computer-aided modeling of activity and selectivity of quinazolinones as noncompetitive NMDA receptor antagonists

Dokl Biochem Biophys. 2012 Mar-Apr:443:118-22. doi: 10.1134/S1607672912020159. Epub 2012 May 5.

Authors

E V Radchenko¹, D S Karlov, V A Palyulin, N S Zefirov, V M Pentkovski

Affiliation

¹ Department of Chemistry, Moscow State University, Moscow, 119991 Russia.

PMID: 22562639
DOI: 10.1134/S1607672912020159

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Binding Sites
Glutamic Acid / metabolism
Models, Theoretical
Quinazolinones / chemistry*
Quinazolinones / pharmacology*
Receptors, N-Methyl-D-Aspartate / antagonists & inhibitors*
Structure-Activity Relationship*

Substances

Quinazolinones
Receptors, N-Methyl-D-Aspartate
Glutamic Acid