Looking at the trees in the central forest: a new pallidal-striatal cell type

Ana M Vicente; Rui M Costa

doi:10.1016/j.neuron.2012.06.003

Looking at the trees in the central forest: a new pallidal-striatal cell type

Neuron. 2012 Jun 21;74(6):967-9. doi: 10.1016/j.neuron.2012.06.003.

Authors

Ana M Vicente¹, Rui M Costa

Affiliation

¹ Champalimaud Neuroscience Programme, Champalimaud Center for the Unknown, Av. De Brasília, 1400-038 Lisbon, Lisbon, Portugal.

PMID: 22726827
DOI: 10.1016/j.neuron.2012.06.003

Abstract

The glopus pallidus is a central nucleus of the basal ganglia, pivotal to their function in health and disease. In this issue of Neuron, Mallet et al. (2012) reveal that this structure is more diverse than previously thought, and identify a novel cell type that projects from pallidum to striatum providing massive GABAergic innervation. These findings invite new views on basal ganglia processing.

Publication types

Comment

MeSH terms

Animals
Basal Ganglia / metabolism*
Corpus Striatum / metabolism*
Enkephalins / metabolism*
Globus Pallidus / metabolism*
Neurons / metabolism*
Parvalbumins / metabolism*
Protein Precursors / metabolism*

Substances

Enkephalins
Parvalbumins
Protein Precursors
preproenkephalin