Abstract
A BODIPY-based selective thiophenol probe capable of discriminating aliphatic thiols is reported. The fluorescence off-on effect upon reaction with thiol is elucidated with theoretical calculations. The sensing of thiophenol is associated with a color change from red to yellow and 63-fold enhancement in green fluorescence. Application of the probe for selective thiophenol detection is demonstrated by live cell imaging.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Boron Compounds / chemistry*
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Colorimetry*
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Fluorescent Dyes / chemistry*
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HeLa Cells
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Humans
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Hydrogen-Ion Concentration
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Models, Theoretical
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Phenols / analysis*
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Quantum Theory
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Sulfhydryl Compounds / analysis*
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Sulfhydryl Compounds / chemistry
Substances
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4,4-difluoro-4-bora-3a,4a-diaza-s-indacene
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Boron Compounds
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Fluorescent Dyes
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Phenols
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Sulfhydryl Compounds
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thiophenol