Oral manifestations of psoriasis. Clinical presentation and management

N Y State Dent J. 2012 Apr;78(3):14-8.

Abstract

Psoriasis is a chronic immune-mediated disease of unknown etiology that affects the skin and mucous membranes. According to the National Institutes of Health (NIH), approximately five million Americans, 3% of the population, have been diagnosed with psoriasis. Oral manifestations of psoriasis are less well recognized than skin lesions, and treatment for oral lesions is not standardized. This article will review the clinical presentation of skin and mucous membrane psoriasis, along with the therapeutic modalities available to oral health-care providers.

MeSH terms

  • Alefacept
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Antibodies, Monoclonal / therapeutic use
  • Antibodies, Monoclonal, Humanized
  • Carboxymethylcellulose Sodium / analogs & derivatives
  • Carboxymethylcellulose Sodium / therapeutic use
  • Diphenhydramine / therapeutic use
  • Etanercept
  • Glossitis, Benign Migratory / drug therapy
  • Glossitis, Benign Migratory / etiology*
  • Glossitis, Benign Migratory / pathology
  • Humans
  • Immunoglobulin G / therapeutic use
  • Immunosuppressive Agents / therapeutic use
  • Infliximab
  • Lip Diseases / drug therapy
  • Lip Diseases / pathology
  • Methotrexate / therapeutic use
  • Mouth Diseases / drug therapy*
  • Mouth Diseases / etiology*
  • Mouth Diseases / pathology
  • Mouth Mucosa / pathology
  • Palliative Care
  • Psoriasis / complications*
  • Psoriasis / drug therapy
  • Receptors, Tumor Necrosis Factor / therapeutic use
  • Recombinant Fusion Proteins / therapeutic use

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Humanized
  • Immunoglobulin G
  • Immunosuppressive Agents
  • Receptors, Tumor Necrosis Factor
  • Recombinant Fusion Proteins
  • Orabase
  • Diphenhydramine
  • Infliximab
  • Alefacept
  • Carboxymethylcellulose Sodium
  • Etanercept
  • efalizumab
  • Methotrexate