Post-transplant critical care outcomes for pediatric multivisceral and intestinal transplant patients

Pediatr Transplant. 2012 Nov;16(7):788-95. doi: 10.1111/j.1399-3046.2012.01765.x. Epub 2012 Jul 27.

Abstract

This study reviews the post-operative management of pediatric intestinal transplant patients at a single center with reporting of standard PICU benchmarks for quality of care. It is a retrospective, descriptive, chart review describing our institution's experience between 2006 and 2010. Twenty patients were included. Median age at transplant was 1.6 yr. Median length of PICU stay was 12 days. Median ventilation time was two days. Median time for continuous sedation infusion was two days, with median continuous pain medication infusion of three days. All patients were placed on parental nutrition and started on enteral feedings between days 3 and 4. Forty percent of patients required hemodynamic support. Only 35% of patients required insulin therapy. Diuretics were frequently used in this patient population. There were no episodes of early rejection. The survival rate to PICU discharge was 95%. Our institution's experience over the past four yr has been very successful with a short duration of mechanical ventilation, limited use of pain and sedation drips, early initiation of enteral feedings, minimal hemodynamic support, and a low mortality rate to PICU discharge despite a preponderance of complex MVTx recipients.

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Critical Care / methods*
  • Female
  • Hemodynamics
  • Humans
  • Infant
  • Intensive Care Units, Pediatric
  • Intestines / transplantation*
  • Male
  • Pain Management
  • Pediatrics / methods
  • Postoperative Period
  • Respiration, Artificial
  • Retrospective Studies
  • Time Factors
  • Treatment Outcome