[Immunophenotype of lymphocytic infiltrate in mycosis fungoides at the plaque stage and at the tumor stage. A comparative study]

G Ital Dermatol Venereol. 1990 Aug;125(7-8):313-7.
[Article in Italian]

Abstract

An immunohistochemical study of 18 cases of mycosis fungoides (8 cases in tumor stage, 10 in plaque stage) is reported. Seven immunohistochemical parameters were set to evaluate the immunophenotype of the lymphocytes int he two stages of the disease. The results showed loss of differentiation and marked activation of the neoplastic lymphocytes with the progression of the disease from plaque to tumor stage.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Antibodies, Monoclonal
  • Humans
  • Immunohistochemistry
  • Immunophenotyping*
  • Lymphocytes / immunology*
  • Mycosis Fungoides / immunology*
  • Mycosis Fungoides / pathology
  • Skin / pathology
  • Skin Neoplasms / immunology*
  • Skin Neoplasms / pathology

Substances

  • Antibodies, Monoclonal