From neuroanatomy to behavior: central integration of peripheral signals regulating feeding behavior

Nat Neurosci. 2012 Oct;15(10):1350-5. doi: 10.1038/nn.3217. Epub 2012 Sep 25.

Abstract

Over the past two centuries, prevalent models of energy and glucose homeostasis have emerged from careful anatomical descriptions in tandem with an understanding of cellular physiology. More recent technological advances have culminated in the identification of peripheral and central factors that influence neural circuits regulating metabolism. This Review highlights contributions to our understanding of peripheral and central factors regulating food intake and energy expenditure.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Brain / anatomy & histology*
  • Brain / physiology*
  • Cholecystokinin
  • Eating / physiology
  • Energy Metabolism / physiology*
  • Feeding Behavior / physiology*
  • Ghrelin / physiology
  • Glucagon-Like Peptide 1 / physiology
  • Humans
  • Insulin / pharmacology
  • Leptin / physiology
  • Melanocortins / physiology
  • Models, Neurological
  • Neural Pathways / anatomy & histology
  • Neural Pathways / physiology
  • Synaptic Transmission / physiology

Substances

  • Ghrelin
  • Insulin
  • Leptin
  • Melanocortins
  • Glucagon-Like Peptide 1
  • Cholecystokinin