Eremophilane derivatives from Senecio dianthus

J Nat Med. 2013 Oct;67(4):711-8. doi: 10.1007/s11418-012-0728-x. Epub 2012 Nov 29.

Abstract

From the aerial parts of Senecio dianthus, five eremophilane glucosides (1, 2, 4-6) and one new eremophilenolide (7) were isolated, together with sixteen known compounds (3, 8-22). Their structures and relative configurations were elucidated on the basis of extensive spectroscopic analysis, including HR-ESI-MS, X-ray, CD, 1D- and 2D-NMR experiments.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Line, Tumor
  • Glucosides / chemistry*
  • Glucosides / toxicity
  • Humans
  • Magnetic Resonance Spectroscopy
  • Naphthalenes / chemistry*
  • Naphthalenes / toxicity
  • Polycyclic Sesquiterpenes
  • Senecio / chemistry*
  • Sesquiterpenes

Substances

  • Glucosides
  • Naphthalenes
  • Polycyclic Sesquiterpenes
  • Sesquiterpenes
  • eremophilane compounds