Abstract
PM2 is an Aeromonas-specific bacteriophage isolated on A. hydrophila strain AH-3. The bacteriophage receptor for this phage was found to be the lipopolysaccharide (LPS), specifically a low-molecular weight LPS fraction (LPS-core oligosaccharides). Mutants resistant to this phage were isolated and found to be devoid of LPS O-antigen and altered in the LPS-core. No other outer-membrane (OM) molecules appeared to be involved in phage binding.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Aeromonas* / metabolism
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Bacteriophages / isolation & purification*
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Bacteriophages / metabolism
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Bacteriophages / ultrastructure
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Electrophoresis, Polyacrylamide Gel
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Lipopolysaccharides / analysis
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Lipopolysaccharides / metabolism*
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Microscopy, Electron
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Mutation
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Receptors, Virus / analysis
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Receptors, Virus / metabolism*
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Temperature
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Viral Plaque Assay
Substances
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Lipopolysaccharides
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Receptors, Virus