[The effect of plant aromatic substances on the activity of various enzymes in the rat blood and liver]

Vopr Med Khim. 1990 Jan-Feb;36(1):31-3.
[Article in Russian]

Abstract

Enzymatic activity was studied in blood plasma, erythrocytes and liver tissue homogenate of rats treated with vegetable aromatic substances. 60 rats were kept within 3 months in atmosphere containing naturally occurring concentrations of monarde ester oil. Control animals were maintained in usual atmosphere of vivarium. In liver tissues of control animals glycolytic processes predominated as shown by the data on increased activities of lactate- and glucose-6-phosphate dehydrogenases. At the same time, activity of soluble microsomal enzyme acetyl esterase was decreased in liver tissue, while activity of these esterases was increased in blood plasma, thus suggesting that membrane structures were destabilized. Aromatic fractions of monarde ester oil, introduced into atmosphere, contributed to normalization of the enzymatic reactions studied.

Publication types

  • English Abstract

MeSH terms

  • Acetylesterase / blood
  • Acetylesterase / metabolism
  • Animals
  • Environmental Exposure
  • Erythrocytes / enzymology*
  • Glucosephosphate Dehydrogenase / blood
  • Glucosephosphate Dehydrogenase / metabolism
  • L-Lactate Dehydrogenase / blood
  • L-Lactate Dehydrogenase / metabolism
  • Liver / enzymology*
  • Malate Dehydrogenase / blood
  • Malate Dehydrogenase / metabolism
  • Male
  • Oils, Volatile / pharmacology*
  • Plant Oils / pharmacology*
  • Rats
  • Rats, Inbred Strains

Substances

  • Oils, Volatile
  • Plant Oils
  • L-Lactate Dehydrogenase
  • Malate Dehydrogenase
  • Glucosephosphate Dehydrogenase
  • Acetylesterase