Sensory evaluation of the taste of berberine hydrochloride using an Electronic Tongue

Fitoterapia. 2013 Apr:86:137-43. doi: 10.1016/j.fitote.2013.02.010. Epub 2013 Feb 26.

Abstract

Background: The "Electronic Tongue" is an instrument that can be trained to screen the taste attributes of formulations within a rapid timeframe when used in conjunction with sensory panel taste assessment data.

Purpose: The purpose of this research was to demonstrate that a sensory instrument for taste (e-Tongue) could be used to evaluate the bitterness of berberine hydrochloride from Chinese medicinal herbs.

Methods: Several flavorful native compounds were tested by the e-Tongue. Data from a human sensory panel was collected to train the e-Tongue. The e-Tongue was then used to establish the correlation between data from the sensory panel, and to predict the bitterness scores of berberine hydrochloride.

Results: The e-Tongue showed different response patterns for different tastes or strengths of flavor compounds. No significant differences were found between the results of the e-Tongue and the sensory taste panel.

Conclusions: The e-Tongue could be used to evaluate the effect of bitterness of berberine hydrochloride. Therefore, e-Tongues showed potential to replace sensory panel evaluations in future experiments regarding Chinese traditional medicine.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't
  • Validation Study

MeSH terms

  • Berberine / analysis*
  • Biosensing Techniques / methods*
  • Chemistry, Pharmaceutical
  • Computing Methodologies
  • Drugs, Chinese Herbal / chemistry*
  • Electronics*
  • Humans
  • Reproducibility of Results
  • Taste Perception
  • Taste*
  • Technology, Pharmaceutical / methods*
  • Tongue*

Substances

  • Drugs, Chinese Herbal
  • Berberine