Impact of endografting on the thoracic aortic anatomy: comparative analysis of the aortic geometry before and after the endograft implantation

Cardiovasc Intervent Radiol. 2014 Feb;37(1):69-76. doi: 10.1007/s00270-013-0601-7. Epub 2013 Mar 13.

Abstract

Purpose: Although the widespread acceptance of thoracic endovascular aortic repair (TEVAR) as a first-line treatment option for a multitude of thoracic aortic diseases, little is known about the consequences of the device implantation on the native aortic anatomy. We propose a comparative analysis of the pre- and postoperative geometry on a clinical series of patients and discuss the potential clinical implications

Methods: CT pre- and postoperative acquisitions of 30 consecutive patients treated by TEVAR for different pathologies (20 thoracic aortic aneurysms, 6 false aneurysms, 3 penetrating ulcers, 1 traumatic rupture) were used to model the vascular geometry. Pre- and postoperative geometries were compared for each patient by pairing and matching the 3D models. An implantation site was identified, and focal differences were detected and described.

Results: Segmentation of the data sets was successfully performed for all 30 subjects. Geometry differences between the pre- and postoperative meshes were depicted in 23 patients (76 %). Modifications at the upper implantation site were detected in 14 patients (47 %), and among them, the implantation site involved the arch (Z0-3) in 11 (78 %).

Conclusion: Modeling the vascular geometry on the basis of imaging data offers an effective tool to perform patient-specific analysis of the vascular geometry before and after the treatment. Future studies will evaluate the consequences of these changes on the aortic function.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Aorta, Thoracic / anatomy & histology
  • Aorta, Thoracic / diagnostic imaging*
  • Aorta, Thoracic / surgery*
  • Aortic Diseases / diagnostic imaging*
  • Aortic Diseases / surgery*
  • Blood Vessel Prosthesis Implantation / methods*
  • Endovascular Procedures / methods*
  • Female
  • Humans
  • Imaging, Three-Dimensional
  • Male
  • Middle Aged
  • Radiographic Image Interpretation, Computer-Assisted
  • Stents
  • Tomography, X-Ray Computed
  • Treatment Outcome