Implant-supported oral rehabilitation of a patient with pemphigus vulgaris: a clinical report

J Prosthodont. 2013 Oct;22(7):581-586. doi: 10.1111/jopr.12050. Epub 2013 Apr 1.

Abstract

Pemphigus vulgaris (PV) is a rare mucocutaneous vesiculobullous disease characterized by the development of autoantibodies against the desmosomal proteins. Current treatment is largely based on systemic immunosuppression using systemic corticosteroids. Immunosuppressive drugs used in the treatment of the disease may increase the risk of infection and delayed healing, which are of concern in dental treatment procedures in this group of patients. The clinical outcomes of implants in PV have not been investigated. We present a case of PV rehabilitated with an implant-supported prosthesis with a 32-month follow-up and discuss the important points in the surgical and prosthodontic phases.

Keywords: Pemphigus vulgaris; dental implant; overdenture prosthesis.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Alveolar Bone Loss / diagnosis
  • Dental Care for Chronically Ill
  • Dental Implantation, Endosseous / methods
  • Dental Prosthesis, Implant-Supported*
  • Denture Design
  • Denture Retention
  • Denture, Complete, Lower*
  • Denture, Overlay*
  • Female
  • Follow-Up Studies
  • Humans
  • Mouth Mucosa / pathology
  • Oral Ulcer / etiology
  • Osseointegration / physiology
  • Pemphigus / complications*
  • Tongue Diseases / etiology
  • Treatment Outcome