A mechanistic approach to preventing schizophrenia in at-risk individuals

Bita Moghaddam

doi:10.1016/j.neuron.2013.03.024

A mechanistic approach to preventing schizophrenia in at-risk individuals

Neuron. 2013 Apr 10;78(1):1-3. doi: 10.1016/j.neuron.2013.03.024.

Author

Bita Moghaddam¹

Affiliation

¹ Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA. bita@pitt.edu

PMID: 23583102
DOI: 10.1016/j.neuron.2013.03.024

Abstract

In this issue of Neuron, Schobel et al. (2013) report that excess hippocampal glutamate may cause transition to psychosis in individuals at high risk for schizophrenia. Their data has implications for prevention strategies and why stress often precipitates this transition.

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Abstract

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