In the Rancho Bernardo, California population of older adults, the age-adjusted prevalence rate of self-reported arthritis was higher in women than men for all types combined (38.6 vs. 22.3%, p less than 0.05), and for osteoarthritis (18.1 vs 12.9%). Men and women with osteoarthritis and disabling arthritis were significantly more likely to report co-morbid conditions. Women with osteoarthritis were significantly less likely to drink alcohol and more likely to be taking estrogen replacement therapy. At 15 years of follow up, mortality rates were not significantly increased in men or women with arthritis or osteoarthritis compared to those without arthritis.