Integrating global and national knowledge to select medicines for children: the Ghana National Drugs Programme

PLoS Med. 2013;10(5):e1001449. doi: 10.1371/journal.pmed.1001449. Epub 2013 May 21.

Abstract

David Sinclair and colleagues discuss their experience at the Ghana National Drugs Programme reviewing the international evidence base for five priority pediatric medicines and report that applying the global recommendations to Ghana was not straightforward for any of the five medicines.

Please see later in the article for the Editors' Summary

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Age Factors
  • Attitude of Health Personnel
  • Child
  • Child Health Services* / economics
  • Clinical Competence
  • Cost-Benefit Analysis
  • Decision Support Techniques*
  • Developing Countries
  • Drug Costs
  • Drug Information Services*
  • Drug Therapy / economics
  • Drug-Related Side Effects and Adverse Reactions
  • Evidence-Based Medicine
  • Ghana
  • Health Knowledge, Attitudes, Practice*
  • Humans
  • Patient Selection*
  • Practice Patterns, Physicians'*
  • Residence Characteristics
  • Risk Assessment
  • Risk Factors

Grants and funding

This project was funded by the Bill & Melinda Gates Foundation through the Better Medicines for Children Project co-ordinated by the World Health Organization. DS and PG receive funding from the UK Department for International Development via the Effective Healthcare Research Consortium. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.