PXR-ALAS1: a key regulatory pathway in liver toxicity induced by isoniazid-rifampicin antituberculosis treatment

Clin Res Hepatol Gastroenterol. 2013 Nov;37(5):439-41. doi: 10.1016/j.clinre.2013.06.010. Epub 2013 Jul 31.

Authors

Said Lyoumi¹, Thibaud Lefebvre, Zoubida Karim, Laurent Gouya, Hervé Puy

Affiliation

¹ Université Versailles-Saint-Quentin-en-Yvelines, Guyancourt, France; Inserm U773, université Paris-Diderot, centre de recherche biomédicale Bichat-Beaujon, site Bichat, Paris, France.

PMID: 23916555
DOI: 10.1016/j.clinre.2013.06.010

No abstract available

Publication types

Editorial
Comment

MeSH terms

Animals
Antitubercular Agents / adverse effects*
Chemical and Drug Induced Liver Injury / etiology*
Humans
Isoniazid / adverse effects*
Male
Receptors, Steroid / drug effects*
Rifampin / adverse effects*

Substances

Antitubercular Agents
Receptors, Steroid
Isoniazid
Rifampin