Conundrum of sudden cardiac death: making sense of missense

Circ Arrhythm Electrophysiol. 2013 Aug;6(4):e58-63. doi: 10.1161/CIRCEP.113.000553.
No abstract available

Keywords: Mahaim pathway; Wolff–Parkinson–White syndrome; accessory pathway; death, sudden, cardiac; genetic testing.

Publication types

  • Case Reports

MeSH terms

  • Accessory Atrioventricular Bundle / etiology
  • Accessory Atrioventricular Bundle / genetics
  • Accessory Atrioventricular Bundle / physiopathology
  • Adult
  • Atrial Fibrillation / etiology
  • Atrial Fibrillation / genetics
  • Atrial Fibrillation / physiopathology
  • Cardiopulmonary Resuscitation
  • Catheter Ablation
  • DNA Mutational Analysis
  • Death, Sudden, Cardiac / etiology*
  • Death, Sudden, Cardiac / prevention & control
  • Defibrillators
  • Electric Countershock / instrumentation
  • Electrocardiography
  • Electrophysiologic Techniques, Cardiac
  • Exercise
  • Female
  • Genetic Predisposition to Disease
  • Humans
  • Hypertrophy, Right Ventricular / etiology
  • Hypertrophy, Right Ventricular / genetics
  • Hypertrophy, Right Ventricular / physiopathology
  • Mutation, Missense*
  • Out-of-Hospital Cardiac Arrest / etiology*
  • Out-of-Hospital Cardiac Arrest / genetics
  • Out-of-Hospital Cardiac Arrest / physiopathology
  • Out-of-Hospital Cardiac Arrest / therapy
  • Phenotype
  • Plakophilins / genetics*
  • Predictive Value of Tests
  • Risk Factors
  • Treatment Outcome
  • Ventricular Fibrillation / etiology
  • Ventricular Fibrillation / genetics
  • Ventricular Fibrillation / physiopathology

Substances

  • PKP2 protein, human
  • Plakophilins