Do US ambient air lead levels have a significant impact on childhood blood lead levels: results of a national study

J Environ Public Health. 2013:2013:278042. doi: 10.1155/2013/278042. Epub 2013 Aug 1.

Abstract

Introduction: Although lead paint and leaded gasoline have not been used in the US for thirty years, thousands of US children continue to have blood lead levels (BLLs) of concern.

Methods: We investigated the potential association of modeled air lead levels and BLLs ≥ 10 μ g/dL using a large CDC database with BLLs on children aged 0-3 years. Percent of children with BLLs ≥ 10 μ g/dL (2000-2007) by county and proportion of pre-50 housing and SES variables were merged with the US EPA's National Air Toxics Assessment (NATA) modeled air lead data.

Results: The proportion with BLL ≥ 10 μ g/dL was 1.24% in the highest air lead counties, and the proportion with BLL ≥ 10 μ g/dL was 0.36% in the lowest air lead counties, resulting in a crude prevalence ratio of 3.4. Further analysis using multivariate negative binomial regression revealed that NATA lead was a significant predictor of % BLL ≥ 10 μ g/dL after controlling for percent pre-l950 housing, percent rural, and percent black. A geospatial regression revealed that air lead, percent older housing, and poverty were all significant predictors of % BLL ≥ 10 μ g/dL.

Conclusions: More emphasis should be given to potential sources of ambient air lead near residential areas.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Air Pollutants / blood*
  • Binomial Distribution
  • Child, Preschool
  • Environmental Exposure*
  • Environmental Monitoring
  • Humans
  • Infant
  • Lead / blood*
  • Lead Poisoning / blood
  • Lead Poisoning / epidemiology*
  • Lead Poisoning / etiology
  • Multivariate Analysis
  • Prevalence
  • United States / epidemiology

Substances

  • Air Pollutants
  • Lead