In vitro activity of temocillin against multidrug-resistant clinical isolates of Escherichia coli, Klebsiella spp. and Enterobacter spp., and evaluation of high-level temocillin resistance as a diagnostic marker for OXA-48 carbapenemase

J Antimicrob Chemother. 2014 Feb;69(2):564-7. doi: 10.1093/jac/dkt383. Epub 2013 Sep 29.

Authors

Neil Woodford¹, Rachel Pike, Daniele Meunier, Richard Loy, Robert Hill, Katie L Hopkins

Affiliation

¹ Antimicrobial Resistance and Healthcare Associated Infections (AMRHAI) Reference Unit, Public Health England, London NW9 5EQ, UK.

PMID: 24080500
DOI: 10.1093/jac/dkt383

No abstract available

Keywords: ESBLs; Enterobacteriaceae; KPC; NDM; VIM.

Publication types

Letter

MeSH terms

Bacterial Proteins / isolation & purification
Drug Resistance, Multiple, Bacterial / drug effects*
Drug Resistance, Multiple, Bacterial / physiology
Enterobacter / drug effects*
Enterobacter / isolation & purification
Escherichia coli / drug effects*
Escherichia coli / isolation & purification
Humans
Klebsiella / drug effects*
Klebsiella / isolation & purification
Microbial Sensitivity Tests / methods
Penicillins / pharmacology*
beta-Lactamases* / isolation & purification

Substances

Bacterial Proteins
Penicillins
temocillin
beta-Lactamases
carbapenemase
oxacillinase