The aim of this study was to examine the lived experiences of Jordanian patients with chronic kidney disease who received hemodialysis. Qualitative interviews were conducted to identify patients' lived experiences. Transcripts analyzed led to seven common themes: lifestyle change, time wasted, symptom-related suffering, marital and family role disruption, religious commitment disruption, motivators to alleviate stressors, and experience of healthcare providers' support. Findings revealed areas where nurses and other healthcare providers can improve care for this patient population and for patients with other chronic illnesses.