Strategies used by Yersinia enterocolitica to evade killing by the host: thinking beyond Yops

Mahesh Shanker Dhar; Jugsharan Singh Virdi

doi:10.1016/j.micinf.2013.11.002

Strategies used by Yersinia enterocolitica to evade killing by the host: thinking beyond Yops

Microbes Infect. 2014 Feb;16(2):87-95. doi: 10.1016/j.micinf.2013.11.002. Epub 2013 Nov 15.

Authors

Mahesh Shanker Dhar¹, Jugsharan Singh Virdi²

Affiliations

¹ Microbial Pathogenicity Laboratory, Department of Microbiology, University of Delhi South Campus, Benito Juarez Road, New Delhi 110 021, India.
² Microbial Pathogenicity Laboratory, Department of Microbiology, University of Delhi South Campus, Benito Juarez Road, New Delhi 110 021, India. Electronic address: virdi_dusc@rediffmail.com.

PMID: 24246617
DOI: 10.1016/j.micinf.2013.11.002

Abstract

Yersinia enterocolitica is an important gastrointestinal pathogen. Its pathogenicity has been attributed primarily to the plasmid encoded Yersinia outer proteins or Yops that are known to subvert the immune system. This review, however, highlights the role of Yop-independent mechanisms that help Y. enterocolitica evade immune system and contribute significantly to its survival in the host.

Keywords: Immune evasion; Serum resistance; Yersinia enterocolitica.

Publication types

Review

MeSH terms

Bacterial Outer Membrane Proteins / immunology
Host-Pathogen Interactions
Humans
Immune Evasion*
Microbial Viability
Plasmids
Virulence Factors / immunology*
Yersinia enterocolitica / immunology*
Yersinia enterocolitica / pathogenicity*

Substances

Bacterial Outer Membrane Proteins
Virulence Factors