[Choroidal neovascularization secondary to angioid streaks: A familial case report]

Abstract

Case report: We report a familial case of 2 brothers that suffered choroidal neovascularization (CNV) secondary to angioid streaks. They were both treated with a monthly intravitreal injection of ranibizumab (Lucentis(®)) for 3 months. Visual acuity was stabilized and fluorescein angiography revealed complete resolution of CNV. Neither recurrent CNV lesion nor new hemorrhages were reported during the follow-up period.

Discussion: The use of intravitreal ranibizumab for the treatment of CNV in patients with angioid streaks has shown favorable results. However, further studies with a longer follow-up and larger number of patients are necessary to more precisely determine the results of this therapy.

Keywords: Angioid streaks; Choroidal neovascularization; Estrías angioides; Lucentis; Neovascularización coroidea; Pseudoxanthoma elasticum; Pseudoxantoma elástico; Ranibizumab.