Castleman's Disease: a rare finding in a pediatric neck

Faisal Zawawi; Rickul Varshney; David G Haegert; Sam J Daniel

doi:10.1016/j.ijporl.2013.11.015

Castleman's Disease: a rare finding in a pediatric neck

Int J Pediatr Otorhinolaryngol. 2014 Feb;78(2):370-2. doi: 10.1016/j.ijporl.2013.11.015. Epub 2013 Nov 25.

Authors

Faisal Zawawi¹, Rickul Varshney², David G Haegert³, Sam J Daniel⁴

Affiliations

¹ Department of Otolaryngology - Head and Neck Surgery, McGill University, Montreal, QC, Canada; King Abdulaziz University, Jeddah, Saudi Arabia. Electronic address: faisalzawawi@gmail.com.
² Department of Otolaryngology - Head and Neck Surgery, McGill University, Montreal, QC, Canada.
³ Department of Pathology, McGill University, Montreal, QC, Canada.
⁴ Department of Otolaryngology - Head and Neck Surgery, McGill University, Montreal, QC, Canada. Electronic address: sam.daniel@mcgill.ca.

PMID: 24332608
DOI: 10.1016/j.ijporl.2013.11.015

Abstract

Castleman's Disease is a rare lymphoproliferative disorder. In the literature, only 29 cases, associated with the neck presentation in children, have been reported. This is another case report regarding a 5-year old child who presented with a persistent cervical lymphadenopathy. Final pathology, after undergoing exploratory neck dissection and surgical excision, revealed Castleman's Disease. This report, augmented with a literature review of all the 29 cases, compares the clinical course of this patient with the other cases. In conclusion, although Castleman's Disease carries a favorable prognosis in children, surgical excision is recommended to confirm the diagnosis and to rule out other causes.

Keywords: Castleman; Cervical; Lymphadenopathy; Pediatric; Surgery.

Publication types

Case Reports
Review

MeSH terms

Castleman Disease / diagnosis*
Castleman Disease / surgery
Child, Preschool
Humans
Male
Neck / pathology*
Neck / surgery
Neck Dissection / methods*