An imaging approach to diffuse white matter changes

Nilesh K Desai; Mark E Mullins

doi:10.1016/j.rcl.2013.11.006

An imaging approach to diffuse white matter changes

Radiol Clin North Am. 2014 Mar;52(2):263-78. doi: 10.1016/j.rcl.2013.11.006. Epub 2013 Dec 28.

Authors

Nilesh K Desai¹, Mark E Mullins²

Affiliations

¹ Division of Neuroradiology, Department of Radiology and Imaging Sciences, Emory University School of Medicine, 1364 Clifton Road Northeast, EUH B115, Atlanta, GA 30322, USA; Children's Healthcare of Atlanta at Egleston and Town Center, Atlanta, GA 30329, USA. Electronic address: nilesh.k.desai@emory.edu.
² Division of Neuroradiology, Department of Radiology and Imaging Sciences, Emory University School of Medicine, 1364 Clifton Road Northeast, Room D125A, Atlanta, GA 30322, USA.

PMID: 24582340
DOI: 10.1016/j.rcl.2013.11.006

Abstract

White matter disorders represent a large, heterogeneous group of disorders that span the continuum of congenital metabolic disorders to acquired processes, such as chronic ischemic microvascular white matter disease. Magnetic resonance imaging has dramatically revolutionized the diagnostic evaluation of patients with these disease processes.

Keywords: Diffuse; Leukodystrophy; Leukoencephalopathy; MRI; T2; White matter.

Publication types

Review

MeSH terms

Demyelinating Diseases / diagnosis
Demyelinating Diseases / pathology
Diagnosis, Differential
Humans
Leukoencephalopathies / diagnosis*
Leukoencephalopathies / pathology
Magnetic Resonance Imaging / methods*
Nerve Fibers, Myelinated / pathology*