Biodegradable stents in gastrointestinal endoscopy

World J Gastroenterol. 2014 Mar 7;20(9):2212-7. doi: 10.3748/wjg.v20.i9.2212.

Abstract

Biodegradable stents (BDSs) are an attractive option to avoid ongoing dilation or surgery in patients with benign stenoses of the small and large intestines. The experience with the currently the only BDS for endoscopic placement, made of Poly-dioxanone, have shown promising results. However some aspects should be improved as are the fact that BDSs lose their radial force over time due to the degradable material, and that can cause stent-induced mucosal or parenchymal injury. This complication rate and modest clinical efficacy has to be carefully considered in individual patients prior to placement of BDSs. Otherwise, the price of these stents therefore it is nowadays an important limitation.

Keywords: Biodegradable stents; Endoscopic placement; Endoscopy; Stenoses; Strictures.

Publication types

  • Review

MeSH terms

  • Absorbable Implants*
  • Constriction, Pathologic
  • Endoscopy, Gastrointestinal / adverse effects
  • Endoscopy, Gastrointestinal / instrumentation*
  • Gastrointestinal Diseases / diagnosis
  • Gastrointestinal Diseases / therapy*
  • Humans
  • Prosthesis Design
  • Stents*
  • Treatment Outcome